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Bioinformatics Team

We are applying computational solutions to contribute to the understanding of inflammatory pathomechanisms and a personalized medical approach, bridging the gap between data, bench and bedside in the rheumatology field.

Our research focuses on providing a better insight on the molecular basis of autoimmune rheumatic diseases using computational approaches. We are working closely with wet-lab scientists and clinicians to generate tailored analysis for experimental data and answer complex biological questions in rheumatology. Use of bioinformatic algorithms for integration of high-throughput and experimental data allows us to perform interdisciplinary research to understand drivers of inflammation and develop a more personalized treatment approach. Several projects are currently ongoing which address the specific role of cell-cell interactions and environmental factors on the transcriptome and epigenome of pathogenic cell types. A major focus lies on epigenetic regulation of cell stability under steady state and autoimmune conditions. Other areas of interests are liquid biopsies and cell-free nucleic acids for biomarker development.

We are continuously looking for highly motivated individuals to join our team.

Team members

As of January 2024.

Anela Tosevska, PhD

Head of the Bioinformatics team

Aruana Hansel Fröse, PhD